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1

The in vitro cytotoxic and apoptotic activity of Triphala—an Indian herbal drug

Swayamjot Kaur, Husheem Michael, Saroj Arora, Pirkko L. Härkönen, Subodh Kumar

Journal:

Journal of Ethnopharmacology

Year:

2005

Language:

english

File:

PDF, 300 KB

english, 2005

2

Monocyte–Macrophage System as a Target for Estrogen and Selective Estrogen Receptor Modulators

PIRKKO L. HÄRKÖNEN, H. KALERVO VÄÄNÄNEN

Journal:

Annals of the New York Academy of Sciences

Year:

2006

Language:

english

File:

PDF, 176 KB

english, 2006

3

Comparative effects of estrogen and antiestrogens on differentiation of osteoblasts in mouse bone marrow culture

Qiang Qu, Pirkko L. Härkönen, H. Kalervo Väänänen

Journal:

Journal of Cellular Biochemistry

Year:

1999

Language:

english

File:

PDF, 108 KB

english, 1999

4

Expression of fibroblast growth factor (FGF)-8 isoforms and FGF receptors in human ovarian tumors

Eeva Valve, Paula Martikainen, Jani Seppänen, Sanna Oksjoki, Susanna Hinkka, Leena Anttila, Seija Grenman, Pekka Klemi, Pirkko Härkönen

Journal:

International Journal of Cancer

Year:

2000

Language:

english

File:

PDF, 630 KB

english, 2000

5

Quantitative detection of cell surface protein expression by time-resolved fluorimetry

Roope J. Huttunen, Tomás C. O'Riordan, Pirkko L. Härkönen, Juhani T. Soini, Niko J. Meltola, Pekka E. Hänninen, Aleksi E. Soini

Journal:

Year:

2007

Language:

english

File:

PDF, 293 KB

english, 2007

6

VEGF-C induced lymphangiogenesis is associated with lymph node metastasis in orthotopic MCF-7 tumors

Mirjami M-T. Mattila, Johanna K. Ruohola, Terhi Karpanen, David G. Jackson, Kari Alitalo, Pirkko L. Härkönen

Journal:

International Journal of Cancer

Year:

2002

Language:

english

File:

PDF, 2.18 MB

english, 2002

7

FGF-8 is involved in bone metastasis of prostate cancer

Maija P. Valta, Johanna Tuomela, Anders Bjartell, Eeva Valve, H. Kalervo Väänänen, Pirkko Härkönen

Journal:

International Journal of Cancer

Year:

2008

Language:

english

File:

PDF, 1.27 MB

english, 2008

8

Immunohistochemical detection of tyrosine phosphatase SHP-1 predicts outcome after radical prostatectomy for localized prostate cancer

Helena Tassidis, Leon J.S. Brokken, Karin Jirström, Roy Ehrnström, Fredrik Pontén, David Ulmert, Anders Bjartell, Pirkko Härkönen, Anette Gjörloff Wingren

Journal:

International Journal of Cancer

Year:

2010

Language:

english

File:

PDF, 1012 KB

english, 2010

9

Estrogen suppression of erbB2 expression is associated with increased growth rate of ZR-75-1 human breast cancer cells in vitro and in nude mice

Anni M. Wärri, Aire M. Laine, Karin E. Majasuo, Kari K. Alitalo, Pirkko L. Härkönen

Journal:

International Journal of Cancer

Year:

1991

Language:

english

File:

PDF, 1.15 MB

english, 1991

10

FGF-8b induces growth and rich vascularization in an orthotopic PC-3 model of prostate cancer

Maija P. Valta, Johanna Tuomela, Heikki Vuorikoski, Niina Loponen, Riina-Minna Väänänen, Kim Pettersson, H. Kalervo Väänänen, Pirkko L. Härkönen

Journal:

Journal of Cellular Biochemistry

Year:

2009

Language:

english

File:

PDF, 544 KB

english, 2009

11

The ERE-like sequence from the promoter region of the testis specific HSP70-related gene is not estrogen responsive.

Zdzislaw Krawczyk, Wolfgang Schmid, Pirkko Härkönen, Piotr Wolniczek

Journal:

Cell Biology International

Year:

1993

File:

PDF, 510 KB

1993

12

Urinary dimethylbenzoic acid excretion as an indicator of occupational exposure to white spirit

Pirkko Pfäffli, H. Härkönen, H. Savolainen

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1985

Language:

english

File:

PDF, 287 KB

english, 1985

13

Loss of heterozygosity in chromosomal region 16q24.3 associated with progression of prostate cancer

Päivi Härkönen, Atte P. Kyllönen, Stig Nordling, Pirkko Vihko

Journal:

Year:

2005

Language:

english

File:

PDF, 202 KB

english, 2005

14

Role of the protein tyrosine phosphatase SHP-1 in Interleukin-6 regulation of prostate cancer cells

Helena Tassidis, Zoran Culig, Anette Gjörloff Wingren, Pirkko Härkönen

Journal:

Year:

2010

Language:

english

File:

PDF, 372 KB

english, 2010

15

Morphological studies on the effect of taxol on cultured human prostatic cancer cells

Matias Röyttä, Kirsi-Marja Laine, Pirkko Härkönen

Journal:

Year:

1987

Language:

english

File:

PDF, 3.92 MB

english, 1987

16

Interaction of male and female sex hormones in cultured rat prostate

Sari I. Mäkelä, Risto S. S. Santti, Pirkko L. Härkönen, Jyrki J. O. Suominen, Paula M. Martikainen

Journal:

Year:

1987

Language:

english

File:

PDF, 2.29 MB

english, 1987

17

Increased expression of cyclooxygenase-2 and nitric oxide synthase-2 in human prostate cancer

Pekka Uotila, Eeva Valve, Paula Martikainen, Marja Nevalainen, Martti Nurmi, Pirkko Härkönen

Journal:

Year:

2001

Language:

english

File:

PDF, 224 KB

english, 2001

18

68Ga-Chloride PET Reveals Human Pancreatic Adenocarcinoma Xenografts in Rats—Comparison with FDG

Tiina Ujula, Satu Salomäki, Anu Autio, Pauliina Luoto, Tuula Tolvanen, Pertti Lehikoinen, Tapio Viljanen, Hannu Sipilä, Pirkko Härkönen, Anne Roivainen

Journal:

Molecular Imaging and Biology

Year:

2010

Language:

english

File:

PDF, 1.03 MB

english, 2010

19

Increased Expression of FGF-8 Isoforms and FGF Receptors in Human Premalignant Prostatic Intraepithelial Neoplasia Lesions and Prostate Cancer

Valve, Eeva M, Nevalainen, Marja T, Nurmi, Martti J, Laato, Matti K, Martikainen, Paula M, Härkönen, Pirkko L

Journal:

Laboratory Investigation

Year:

2001

Language:

english

File:

PDF, 2.03 MB

english, 2001

20

FGF-8b increases angiogenic capacity and tumor growth of androgen-regulated S115 breast cancer cells

Mattila, Mirjami MT, Ruohola, Johanna K, Valve, Eeva M, Tasanen, Merja J, Seppänen, Jani A, Härkönen, Pirkko L

Journal:

Year:

2001

Language:

english

File:

PDF, 726 KB

english, 2001

21

Estrogen and Testosterone Use Different Cellular Pathways to Inhibit Osteoclastogenesis and Bone Resorption

Husheem Michael, Pirkko L Härkönen, H Kalervo Väänänen, Teuvo A Hentunen

Journal:

Journal of Bone and Mineral Research

Year:

2005

Language:

english

File:

PDF, 343 KB

english, 2005

22

The Effects of Tamoxifen and Toremifene on Bone Cells Involve Changes in Plasma Membrane Ion Conductance

Petri Lehenkari, Vilhelmiina Parikka, Timo J Rautiala, Matti Weckström, Johanna Dahllund, Pirkko L Härkönen, H Kalervo Väänänen

Journal:

Journal of Bone and Mineral Research

Year:

2003

Language:

english

File:

PDF, 714 KB

english, 2003

23

Tracer Level Electrophilic Synthesis and Pharmacokinetics of the Hypoxia Tracer [18F]EF5

Olli Eskola, Tove J. Grönroos, Sarita Forsback, Johanna Tuomela, Gaber Komar, Jörgen Bergman, Pirkko Härkönen, Merja Haaparanta, Heikki Minn, Olof Solin

Journal:

Molecular Imaging and Biology

Year:

2012

Language:

english

File:

PDF, 402 KB

english, 2012

24

The expression of matrix receptor syndecan is suppressed in hormonally transformed S115 cells

Sirpa Dahlstedt, Pirkko Härkönen, Markku Jalkanen

Journal:

Cell Differentiation and Development

Year:

1989

Language:

english

File:

PDF, 75 KB

english, 1989

25

Editorial Comment on: Expression and Prognostic Relevance of Annexin A3 in Prostate Cancer

Pirkko Härkönen

Journal:

European Urology

Year:

2008

Language:

english

File:

PDF, 50 KB

english, 2008

26

Editorial Comment on: Stem Cell Characteristics in Prostate Cancer Cell Lines

Pirkko Härkönen

Journal:

European Urology

Year:

2010

Language:

english

File:

PDF, 122 KB

english, 2010

27

Multiparametric luminescence method for quantitative cell surface protein expression analysis and imaging

Roope Huttunen, Juhani Soini, Pirkko Härkönen, Pekka Hänninen, Harri Härmä

Journal:

Journal of Immunological Methods

Year:

2011

Language:

english

File:

PDF, 1.67 MB

english, 2011

28

Fibroblast growth factor 8 increases breast cancer cell growth by promoting cell cycle progression and by protecting against cell death

Emeli M. Nilsson, Leon J.S. Brokken, Pirkko L. Härkönen

Journal:

Experimental Cell Research

Year:

2010

Language:

english

File:

PDF, 2.99 MB

english, 2010

29

Fast growth associated with aberrant vasculature and hypoxia in fibroblast growth factor 8b (FGF8b) over-expressing PC-3 prostate tumour xenografts

Johanna Tuomela, Tove J Grönroos, Maija P Valta, Jouko Sandholm, Aleksi Schrey, Jani Seppänen, Päivi Marjamäki, Sarita Forsback, Ilpo Kinnunen, Olof Solin, Heikki Minn, Pirkko L Härkönen

Journal:

Year:

2010

Language:

english

File:

PDF, 6.05 MB

english, 2010

30

Effects of estradiol and medroxyprogesterone acetate on morphology, proliferation and apoptosis of human breast tissue in organ cultures

Natalija Eigėlienė, Pirkko Härkönen, Risto Erkkola

Journal:

Year:

2006

Language:

english

File:

PDF, 2.08 MB

english, 2006

31

Alendronate decreases orthotopic PC-3 prostate tumor growth and metastasis to prostate-draining lymph nodes in nude mice

Johanna M Tuomela, Maija P Valta, Kalervo Väänänen, Pirkko L Härkönen

Journal:

Year:

2008

Language:

english

File:

PDF, 1.04 MB

english, 2008

32

Overexpression of vascular endothelial growth factor C increases growth and alters the metastatic pattern of orthotopic PC-3 prostate tumors

Johanna Tuomela, Maija Valta, Jani Seppänen, Kati Tarkkonen, H Kalervo Väänänen, Pirkko Härkönen

Journal:

Year:

2009

Language:

english

File:

PDF, 4.36 MB

english, 2009

33

FGF-8 Is Expressed during Specific Phases of Rodent Oocyte and Spermatogonium Development

Eeva Valve, Tarja-Leena Penttilä, Jorma Paranko, Pirkko Härkönen

Journal:

Biochemical and Biophysical Research Communications

Year:

1997

Language:

english

File:

PDF, 674 KB

english, 1997

34

Activation ofFgf8in S115 Mouse Mammary Tumor Cells Is Associated with Genomic Integration of Mouse Mammary Tumor Virus

Eeva M. Valve, Merja J. Tasanen, Johanna K. Ruohola, Pirkko L. Härkönen

Journal:

Biochemical and Biophysical Research Communications

Year:

1998

Language:

english

File:

PDF, 231 KB

english, 1998

35

Temperature-sensitive mutants for steroid-sensitive growth of S115 mouse mammary tumor cells

Pirkko L. Härkönen, Esti I.G. Laaksonen, Eeva M. Valve, Nicola Solic, Philippa D. Darbre

Journal:

Experimental Cell Research

Year:

1990

Language:

english

File:

PDF, 1.70 MB

english, 1990

36

Studies on the inhibition of testosterone action by cycloheximide: Evidence for a protein activator of glucose metabolism in the ventral prostate of the rat

Anja Kuosa, Pirkko Härkönen, R.S. Santti

Journal:

Journal of Steroid Biochemistry

Year:

1977

Language:

english

File:

PDF, 977 KB

english, 1977

37

Androgenic control of glycolysis, the pentose cycle and pyruvate dehydrogenase in the rat ventral prostate

Pirkko Härkönen

Journal:

Journal of Steroid Biochemistry

Year:

1981

Language:

english

File:

PDF, 1.17 MB

english, 1981

38

Glucose stimulation of testosterone-maintained protein synthesis in the rat ventral prostate

Pirkko Härkönen

Journal:

Journal of Steroid Biochemistry

Year:

1983

Language:

english

File:

PDF, 815 KB

english, 1983

39

Calcitonin promotes osteoclast survival in vitro

Katri S. Selander, Pirkko L. Härkönen, Eeva Valve, Jukka Mönkkönen, Ritva Hannuniemi, H.Kalervo Väänänen

Journal:

Molecular and Cellular Endocrinology

Year:

1996

Language:

english

File:

PDF, 1.16 MB

english, 1996

40

Estrogen and bone metabolism

H. Kalervo Väänänen, Pirkko L. Härkönen

Journal:

Year:

1996

Language:

english

File:

PDF, 418 KB

english, 1996

41

α-Trinositol inhibits FGF-stimulated growth of smooth muscle and breast cancer cells

Matti J. Sirén, Maija Vainiomäki, Kalervo Väänänen, Pirkko Härkönen

Journal:

Biochemical and Biophysical Research Communications

Year:

2004

Language:

english

File:

PDF, 377 KB

english, 2004

42

Role of fibroblast growth factor 8 in growth and progression of hormonal cancer

Mirjami M. Mattila, Pirkko L. Härkönen

Journal:

Cytokine & Growth Factor Reviews

Year:

2007

Language:

english

File:

PDF, 420 KB

english, 2007

43

In vitro bioactivity-guided fractionation and characterization of polyphenolic inhibitory fractions from Acacia nilotica (L.) Willd. ex Del.

Kamaljit Kaur, Husheem Michael, Saroj Arora, Pirkko Härkönen, Subodh Kumar

Journal:

Journal of Ethnopharmacology

Year:

2005

Language:

english

File:

PDF, 428 KB

english, 2005

44

Comparative study of the short-term effects of a novel selective estrogen receptor modulator, ospemifene, and raloxifene and tamoxifen on rat uterus

Huili Zheng, Lauri Kangas, Pirkko L Härkönen

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Year:

2004

Language:

english

File:

PDF, 1.05 MB

english, 2004

45

Role of estrogens in development of prostate cancer

Pirkko L. Härkönen, Sari I. Mäkelä

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Year:

2004

Language:

english

File:

PDF, 308 KB

english, 2004

46

Sex specific expression of progesterone receptor in mouse lower urinary tract

Saija Savolainen, Risto Santti, Tomi Streng, Jan-Åke Gustafsson, Pirkko Härkönen, Sari Mäkelä

Journal:

Molecular and Cellular Endocrinology

Year:

2005

Language:

english

File:

PDF, 370 KB

english, 2005

47

Androgen and fibroblast growth factor 8 (FGF8) downregulation of thrombospondin 1 (TSP1) in mouse breast cancer cells

Mirjami M. Mattila, Kati M. Tarkkonen, Jani A. Seppänen, Johanna K. Ruohola, Eeva M. Valve, Pirkko L. Härkönen

Journal:

Molecular and Cellular Endocrinology

Year:

2006

Language:

english

File:

PDF, 364 KB

english, 2006

48

Estrogen and the selective estrogen receptor modulator (SERM) protection against cell death in estrogen receptor alpha and beta expressing U2OS cells

Anu Kallio, Tao Guo, Elisa Lamminen, Jani Seppänen, Lauri Kangas, H. Kalervo Väänänen, Pirkko Härkönen

Journal:

Molecular and Cellular Endocrinology

Year:

2008

Language:

english

File:

PDF, 1.10 MB

english, 2008

49

Inhibition of cancer cell growth by crude extract and the phenolics of Terminalia chebula retz. fruit

Ammar Saleem, Michael Husheem, Pirkko Härkönen, Kalevi Pihlaja

Journal:

Journal of Ethnopharmacology

Year:

2002

Language:

english

File:

PDF, 357 KB

english, 2002

50

Expression of the androgen-dependent MMTV-specific orf gene in Shionogi 115 mouse mammary tumor cells

Eeva M Valve, Johanna K Ruohola, Merja J Tasanen, James F Glover, Philippa D Darbre, Pirkko L Härkönen

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Year:

2001

Language:

english

File:

PDF, 218 KB

english, 2001